This database was originally set up in 2008 by Dror Warschawski (please visit his wonderful http://www.drorlist.com/nmr.html).
Since 2017, we pursue his effort to update this database. The table below provides information about membrane proteins whose structures have been determined by solution and solid-state NMR, to a resolution sufficient to have resulted in a file deposited with the worldwide Protein Data Bank (http://wwpdb.org/). Please help us to keep this table up to date by sending missing information to: a.loquet@iecb.u-bordeaux.fr or b.habenstein@iecb.u-bordeaux.fr
Click here to go to the database of solid-state NMR protein structures.
Last update: Nov-19 2018
Name | Domain | Category | PDB | BMRB | Size | Source | Reconstitution medium | Methods | Reference | Year |
---|---|---|---|---|---|---|---|---|---|---|
Gramicidin | - | a-helical transmembrane | 1MAG | - | 4 kDa/2 | synthetic | lipids | oriented | Ketchem et al., Science | 1993 |
fd coat protein | - | a-helical transmembrane | 1FDM | 5815 | 5 kDa/1 | E. coli | SDS | solution | Almeida and Opella, J. Mol. Biol. | 1997 |
Glycophorin A | Transmembrane domain | a-helical transmembrane | 2KPF | - | 4 kDa/2 | E. coli | isotropic bicelles | solution | MacKenzie et al., Science | 1997 |
Glycophorin A | Transmembrane domain | a-helical transmembrane | 2KPE | - | 4 kDa/2 | E. coli | DPC | solution | MacKenzie et al., Science | 1997 |
Glycophorin A | Transmembrane domain | a-helical transmembrane | 1AFO | - | 4 kDa/2 | E. coli | DPC (40°C) | solution | MacKenzie et al., Science | 1997 |
F1F0 ATP synthase | Subunit c from E Coli | a-helical transmembrane | 1A91 | 4146 | 8 kDa/1 | E. coli (C43) | Chloroform, Methanol, Water | solution | Girvin et al., Biochemistry | 1998 |
F1F0 ATP synthase | Subunit c from E. coli | a-helical transmembrane | 1C0V | 10021 & 15564 | 8 kDa/1 | E. coli (E43) | Chloroform, methanol, water | solution | Girvin et al., J. Biomol. NMR | 1998 |
F1F0 ATP synthase | Subunit b from E Coli | a-helical transmembrane | 1B9U | - | 4 kDa/1 | synthetic | Chloroform, Methanol, Water | solution | Dmitriev et al., J. Biol. Chem. | 1999 |
Neuronal acetylcholine receptor M2 channel | - | a-helical transmembrane | 1CEK | - | 3 kDa/1 | E. coli | lipids | oriented | Opella et al., Nat. Struct. Biol. | 1999 |
F1F0 ATP synthase | A1C12 subcomplex from E. coli (pH 5) | a-helical transmembrane | 1C17 | 4151 | 119 kDa/12 | E. coli | Chloroform, Methanol, Water | solution | Rastogi and Girvin, Nature | 1999 |
Bacteriorhodopsin | Peptide fragments | a-helical transmembrane | 1L0M | - | 23 kDa/1 | synthetic | DMSO | solution | Katragadda et al., Biophys. J. | 2000 |
Bovine Rhodopsin | Intradiskal loop 1 (res 92-293) | a-helical transmembrane | 1EDS | 4655 | 3 kDa/1 | synthetic | DMSO | solution | Yeagle et al., J. Pept. Res. | 2000 |
Bovine Rhodopsin | Intradiskal loop 3 (res 268-293) | a-helical transmembrane | 1EDW | 4653 | 4 kDa/13 | synthetic | DMSO | solution | Yeagle et al., J. Pept. Res. | 2000 |
Bovine Rhodopsin | Intradiskal loop 2 (res 172-205) | a-helical transmembrane | 1EDV | 4654 | 4 kDa/1 | synthetic | DMSO | solution | Yeagle et al., J. Pept. Res. | 2000 |
Bovine Rhodopsin | Res 1-40 | a-helical transmembrane | 1EDX | 4652 | 5 kDa/1 | synthetic | DMSO | solution | Yeagle et al., J. Pept. Res. | 2000 |
Bovine Rhodopsin | Helix 7 | a-helical transmembrane | 1FDF | 4651 | 3 kDa/1 | synthetic | DMSO | solution | Yeagle et al., Mol. Vis. | 2000 |
OmpA | - | Beta-barrels | 1G90 | 19940 | 19 kDa/1 | E. coli | DPC (600 mM; 50°C) | solution | Arora et al., Nat. Struct. Biol. | 2001 |
OmpX | - | Beta-barrels | 1ORM | 4936 | 16 kDa/1 | E. coli | DHPC (200 mM; 30°C) | solution | Fernandez et al., PNAS | 2001 |
Alpha-Factor receptor M6 | Peptide segment of the 6th transmembrane domain | a-helical transmembrane | 1PJD | - | 2 kDa/1 | synthetic | lipids | oriented | Valentine et al., Biopolymers | 2001 |
Antennapedia homeodomain penetratin (3rd helix) | WT | a-helical transmembrane | 1KZ0 | 5289 | 2 kDa/1 | synthetic | Trifluoroethanol | solution | Czajlik et al. , J. Pept. Sci. | 2002 |
Antennapedia homeodomain penetratin (3rd helix) | 4 residue deletion | a-helical transmembrane | 1KZ5 | 5291 | 2 kDa/1 | synthetic | Trifluoroethanol | solution | Czajlik et al., J. Pept. Sci. | 2002 |
Antennapedia homeodomain penetratin (3rd helix) | WT | a-helical transmembrane | 1KZ2 | 5290 | 2 kDa/1 | synthetic | Trifluoroethanol | solution | Czajlik et al., J. Pept. Sci. | 2002 |
F1F0 ATP synthase | D24N61 mutant of subunit c | a-helical transmembrane | 1L6T | 5326 | 8 kDa/1 | E. coli | Chloroform, Methanol, Water | solution | Dmitriev et al., Biochemistry | 2002 |
PagP | - | Beta-barrels | 1MM5 | 6234 | 20 kDa/1 | E. coli | DPC (500 mM; 45°C) | solution | Hwang et al., PNAS | 2002 |
PagP | - | Beta-barrels | 1MM4 | 5557 | 20 kDa/1 | E. coli | OG (200 mM; 45°C) | solution | Hwang et al., PNAS | 2002 |
Influenza hemagglutinin fusion peptide | G8A mutant | Membrane associated proteins | 2LWA | 18617 | 9 kDa/3 | E. coli | DPC | solution | Lorieau et al., PNAS | 2002 |
Light Harvesting 1 beta Subunit (from Rhodobacter sphaeroides) | - | a-helical transmembrane | 1JO5 | 4949 | 5 kDa/1 | Rhodobacter sphaeroides | Zwittergent 3-12 | solution | Sorgen et al., Biochemistry | 2002 |
Influenza M2 proton channel | Residues 22-46 | a-helical transmembrane | 1NYJ | - | 11 kDa/4 | synthetic | lipids (DMPC, 30°C) | oriented | Nishimura et al., Biochemistry | 2002 |
Antennapedia homeodomain penetratin (3rd helix) | W6F, W14F mutant | a-helical transmembrane | 1OMQ | 5542 | 2 kDa/1 | synthetic | isotropic bicelles | solution | Lindberg et al., Eur. J. Biochem. | 2003 |
fd coat protein | - | a-helical transmembrane | 1MZT | 5815 | 5 kDa/1 | E. coli | lipids | oriented | Marassi and Opella, Protein Sci. | 2003 |
HIV Vpu channel | Monomer & trimer | a-helical transmembrane | 1PI7 & 1PI8 & 1PJE | - | 4 kDa/1 | E. coli | lipids | oriented | Park et al., J. Mol. Biol. | 2003 |
Neuronal acetylcholine receptor M2 channel | 2nd transmembrane domain of the beta 2 subunit | a-helical transmembrane | 2K59 | - | 3 kDa/1 | synthetic | DPC | solution | Yushmanov et al, Biochemistry | 2003 |
Transportan | - | a-helical transmembrane | 1SMZ | 6151 | 3 kDa/1 | synthetic | isotropic bicelles (75 mM DMPC; 225 mM DHPC; 37°C) | solution | Barany-Wallje et al., FEBS Lett. | 2004 |
F1F0 ATP synthase | A1C12 subcomplex from E. coli (pH 8) | a-helical transmembrane | 1C99 | 6021 | 119 kDa/12 | E. coli | Chloroform, Methanol, Water | solution | Dmitriev et al., J. Biomol. NMR | 2004 |
OmpX | - | Beta-barrels | 1Q9F | 15201 | 16 kDa/1 | E. coli | DHPC (300mM; 40°C) | solution | Fernandez et al., J. Mol. Biol. | 2004 |
OmpX | Without H-bond constraints | Beta-barrels | 1Q9G | 15201 | 16 kDa/1 | E. coli | DHPC (300mM; 40°C) | solution | Fernandez et al., J. Mol. Biol. | 2004 |
Stannin | - | a-helical transmembrane | 1ZZA | 6715 | 14 kDa/1 | E. coli | SDS | solution and oriented | Buck-Koehntop et al, J. Mol. Biol. | 2005 |
Mercury transporter Mer F | Integral membrane domain | a-helical transmembrane | 1WAZ | - | 6 kDa/1 | E. coli (C43) | SDS (500 mM; 60°C) | solution | Howell et al., Biochemistry | 2005 |
Phospholamban | Unphosphorylated pentamer | a-helical transmembrane | 1ZLL | 4907 | 30 kDa/5 | E. coli | DPC (200 mM; 30°C) | solution | Oxenoid and Cho, PNAS | 2005 |
Phospholamban | C41F | a-helical transmembrane | 1FJK & 1FJP | 4907 | 30 kDa/5 | E. coli | DPC (200 mM; 30°C) | solution | Oxenoid and Cho, PNAS | 2005 |
Mistic membrane-integrating protein | - | Membrane associated proteins | 1YGM | - | 13 kDa/1 | E. coli | LDAO | solution | Roosild et al., Science | 2005 |
KcsA | with Charybdotoxin | a-helical transmembrane | 2A9H | 6728 (methyls) | 71 kDa/4 | E. coli (C41) | DPC (80 mM, 42°C) | solution | Yu et al., Biochemistry | 2005 |
ZetaZeta transmembrane domain | - | a-helical transmembrane | 2HAC | - | 4 kDa/2 | E. coli | DPC/SDS:5/1 (150 mM DPC; 30 mM SDS; 30°C) | solution | Call et al., Cell | 2006 |
OmpA | - | Beta-barrels | 2GE4 | 19940 | 19 kDa/1 | E. coli | DPC (600 mM; 50°C) | solution | Cierpicki et al., JACS | 2006 |
Mercury transporter Mer F | Integral membrane domain | a-helical transmembrane | 2H3O | - | 6 kDa/1 | E. coli (C43) | bicelles, 40°C | oriented | De Angelis et al., JACS | 2006 |
Protegrin-1 | - | a-helical transmembrane | 1ZY6 | - | 4 kDa/2 | synthetic | lipids (POPC) | MAS | Mani et al., Biochemistry | 2006 |
F1F0 ATP synthase | Subunit c from bacillus PS3 | a-helical transmembrane | 1WUO | 6489 | 7 kDa/1 | E. coli | Chloroform, Methanol, Water | solution | Nakano et al., J. Mol. Biol. | 2006 |
Mastoparan | - | Membrane associated proteins | 2CZP | 10001 | 2 kDa/1 | E. coli | DPPC:DPPG=4:1 | MAS | Todokoro et al., Biophys. J. | 2006 |
Penetratin conjugated Gas | Res 374-394 | a-helical transmembrane | 2NZZ | - | 5 kDa/1 | synthetic | DPC (100 mM; 27°C) | solution | Albrizio et al., J. Med. Chem. | 2007 |
Penetratin conjugated Gas | Res 374-394 | a-helical transmembrane | 2O00 | - | 5 kDa/1 | synthetic | SDS (100 mM; 27°C) | solution | Albrizio et al., J. Med. Chem. | 2007 |
Bnip3 transmembrane domain | - | a-helical transmembrane | 2J5D | 7288 | 10 kDa/2 | E. coli | lipid bicelles | solution | Bocharov et al., J. Biol. Chem. | 2007 |
Bnip3 transmembrane domain | - | a-helical transmembrane | 2KA2 | - | 10 kDa/2 | E. coli | detergent micelles with His173-Ser172 intermonomer Hbond restraints | solution | Bocharov et al., J. Biol. Chem. | 2007 |
Bnip3 transmembrane domain | - | a-helical transmembrane | 2KA1 | 16012 | 10 kDa/2 | E. coli | detergent micelles | solution | Bocharov et al., J. Biol. Chem. | 2007 |
Neuronal acetylcholine receptor M2 channel | 1st transmembrane domain of the beta 2 subunit | a-helical transmembrane | 2K58 | - | 4 kDa/1 | synthetic | DPC | solution | Bondarenko et al, Biophys. J. | 2007 |
FXYD4 (CHIF) | - | a-helical transmembrane | 2JP3 | - | 7 kDa/1 | E. coli | SDS | solution | Franzin et al., JACS | 2007 |
Influenza M2 proton channel | Residues 22-46 with amantadine | a-helical transmembrane | 2H95 | - | 8 kDa/4 | synthetic | lipids (DMPC, DMPG, 25°C) | oriented | Hu et al., Biophys. J. | 2007 |
OmpA | With four shortened loops (beta-barrel platform BBP) | Beta-barrels | 2JMM | 15045 | 16 kDa/1 | E. coli | DHPC (37°C) | solution | Johansson et al., Biochemistry | 2007 |
OmpG | - | Beta-barrels | 2JQY | 15426 | 28 kDa/1 | E. coli | DPC (40°C) | solution | Liang & Tamm, PNAS | 2007 |
FXYD1 (Na,K-ATPase Regulatory Protein) | - | a-helical transmembrane | 2JO1 | - | 8 kDa/1 | E. coli | SDS (500 mM; 40°C) | solution | Teriete et al., Biochemistry | 2007 |
MEC-4 mechanosensory ion channel subunit | Cytosolic domain of C. elegans | Membrane associated proteins | 2K2B | 15699 | 13 kDa/1 | E. coli | Zwittergent | solution | - | 2008 |
VDAC-1 | - | Beta-barrels | 2JK4 | - | 32 kDa/1 | E. coli | LDAO 250 mM | solution | Bayrhuber et al., PNAS | 2008 |
EphA1 transmembrane domain | at pH 4.3 and 6.3 | a-helical transmembrane | 2K1L | 15728 | 8 kDa/1 | E. coli | isotropic bicelles (140 mM DHPC; 35 mM DMPC; 40°C) | solution | Bocharov et al., J. Biol. Chem. | 2008 |
EphA1 | Transmembrane domain | a-helical transmembrane | 2K1K | 15728 | 8 kDa/2 | E. coli | isotropic bicelles (140 mM DHPC; 35 mM DMPC; 40°C) | solution | Bocharov et al., J. Biol. Chem. | 2008 |
ErbB2 | Transmembrane segment | a-helical transmembrane | 2JWA | 15231 | 9 kDa/2 | E. coli | isotropic bicelles (140 mM DHPC; 35 mM DMPC; 40°C) | solution | Bocharov et al., J. Biol. Chem. | 2008 |
VDAC-1 | - | Beta-barrels | 2K4T | - | 32 kDa/1 | E. coli | LDAO 300-500 mM | solution | Hiller et al., Science | 2008 |
KCNE1 | - | a-helical transmembrane | 2K21 | - | 16 kDa/1 | E. coli | LMPG (80 mM; 40°C) | solution | Kang et al., Biochemistry | 2008 |
Influenza M2 proton channel | Residues 18-60 with rimantadine inhibitor | a-helical transmembrane | 2RLF | - | 20 kDa/4 | E. coli | DHPC (300 mM; 30°C) | solution | Schnell & Chou. Nature | 2008 |
DsbB | - | a-helical transmembrane | 2K73 | - | 18 kDa/1 | E. coli | DPC, 40°C | solution | Zhou et al., Mol. Cell | 2008 |
DsbB-ubiquinone complex | - | a-helical transmembrane | 2K74 | - | 18 kDa/1 | E. coli | DPC, 40°C | solution | Zhou et al., Mol. Cell | 2008 |
Vasopressin V2 receptor (GPCR) | i3 intracellular loop | a-helical transmembrane | 2JX4 | - | 6 kDa/1 | synthetic | DPC | solution | Bellot et al., J. Mol. Biol. | 2009 |
Influenza M2 proton channel | Residues 22-46 with amantadine | a-helical transmembrane | 2KAD | 16020 | 11 kDa/4 | synthetic | lipids (DLPC) | MAS and oriented | Cady et al., J. Mol. Biol. | 2009 |
v-SNARE Synaptobrevin 2 | - | a-helical transmembrane | 2KOG | - | 13 kDa/1 | E. coli | DPC | solution | Ellena et al., PNAS | 2009 |
A1AO ATP synthase | N-terminal domain of subunit E (E1-52) from Methanocaldococcus jannaschii | a-helical transmembrane | 2KK7 | 16354 | 6 kDa/1 | E. coli | Trifluoroethanol, Water | solution | Gayen et al., J. Bioenerg. Biomembr. | 2009 |
Integrin alphaIIb-beta3 | Shorter construct | a-helical transmembrane | 2K9J | - | 9 kDa/1 | E. coli | isotropic bicelles (385 mM DHPC; 83 mM POPC; 41mM POPS; 30°C) | solution | Lau et al., EMBO J. | 2009 |
Ste2p (GPCR) | Double transmembrane fragment | a-helical transmembrane | 2K9P | - | 9 kDa/1 | E. coli | LPPG (200 mM; 47°C) | solution | Neumoin et al., Biophys. J. | 2009 |
Rv1761c (from Mycobacterium tuberculosis) | - | a-helical transmembrane | 2K3M | 15774 | 17 kDa/1 | E. coli | DPC (150 mM; 50°C) | solution | Page et al., Protein Sci. | 2009 |
Pf1 coat protein | - | a-helical transmembrane | 2KLV | 5877 | 5 kDa/1 | Pseudomonas aeroginusa | DHPC (100 mM; 50°C) | solution | Park et al., JACS | 2009 |
Influenza M2 proton channel | S31N mutant, res 18-60 with rimantadine inhibitor | a-helical transmembrane | 2KUH | - | 20 kDa/4 | E. coli | DHPC (150 mM; 30°C) | solution | Pielak et al., PNAS | 2009 |
Kp OmpA | - | Beta-barrels | 2K0L | 15651 | 22 kDa/1 | E. coli | DHPC (300 mM; 40°C) | solution | Renault et al., J. Mol. Biol. | 2009 |
Phospholamban | - | a-helical transmembrane | 2KB7 | - | 30 kDa/5 | E. coli | DPC (300 mM; 37°C) and lipids | solution, oriented and MAS | Traaseth et al., PNAS | 2009 |
Diacylglycerol Kinase (DAGK) | - | a-helical transmembrane | 2KDC | 15019 & 7340 | 43 kDa/3 | E. coli | DPC, 45°C | solution | Van Horn et al., Science | 2009 |
Influenza B proton channel | - | a-helical transmembrane | 2KIX | - | 15 kDa/4 | E. coli | DHPC (300 mM, 30°C) | solution | Wang et al., Nat. Struct. Mol. Biol. | 2009 |
Integrin alphaIIb-beta3 | - | a-helical transmembrane | 2KNC | - | 15 kDa/1 | E. coli | Acetonitrile, Water, 25°C | solution | Yang et al., PNAS | 2009 |
HNP-1 alpha-defensin | - | a-helical transmembrane | 2KHT | 16254 | 3 kDa/1 | E. coli | microcrystalised outside the lipid membrane | MAS | Zhang et al. J. Mol. Biol. | 2009 |
EphA2 dimer | - | a-helical transmembrane | 2K9Y | 16005 | 9 kDa/2 | E. coli | isotropic bicelles (140 mM DHPC; 35 mM DMPC; 40°C) | solution | Bocharov et al., Biophys. J. | 2010 |
Neuronal acetylcholine receptor M2 channel | Transmembrane domain of the beta 2 subunit + a mutant | a-helical transmembrane | 2KSR | 101528 | 18 kDa/1 | E. coli | Hexafluoro- | solution | Bondarenko et al., Biochim. Biophys. Acta. | 2010 |
KvAP | Voltage-sensing domain from Aeropyrum pernix | a-helical transmembrane | 2KYH | 16957 | 16 kDa/1 | E. coli | c7-DHPC (5mM, 45°C) | solution | Butterwick & MacKinnon, J. Mol. Biol. | 2010 |
Influenza M2 proton channel | Res 22-46 with amantadine | a-helical transmembrane | 2KQT | 16612 | 11 kDa/4 | synthetic | lipids (DMPC) | MAS and oriented | Cady et al., Nature | 2010 |
DAP12 | Transmembrane homodimer | a-helical transmembrane | 2L34 | - | 7 kDa/2 | E. coli | SDS (25 mM) and DPC (250 mM), 30°C | solution | Call et al., Nat. Immunol. | 2010 |
DAP12-NKG2C | Transmembrane heterotrimer | a-helical transmembrane | 2L35 | - | 10 kDa/1 | E. coli | SDS (25 mM) and DPC (250 mM), 30°C | solution | Call et al., Nat. Immunol. | 2010 |
MSI-594 antibacterial peptide | - | a-helical transmembrane | 2L36 | - | 2 kDa/1 | synthetic | Lipopolysaccharide micelles | solution | Domadia et al., JACS | 2010 |
Sensory rhodopsin II | - | a-helical transmembrane | 2KSY | 16678 | 26 kDa/1 | E. coli | c7-DHPC (100 mM; 50°C) | solution | Gautier et al., Nat. Struct. Mol. Biol. | 2010 |
LAH4 Histidine-Rich Peptide | pH 6.1 | a-helical transmembrane | 2KJN | 16332 | 3 kDa/1 | synthetic | DPC | solution | Georgescu et al., Biophys. J | 2010 |
LAH4 Histidine-Rich Peptide | pH 4.1 | a-helical transmembrane | 2KJO | 16332 | 3 kDa/1 | synthetic | DPC | solution | Georgescu et al., Biophys. J | 2010 |
Hepatitis C virus (NS2) | Res 60-99 | a-helical transmembrane | 2KWZ | 16892 | 4 kDa/1 | synthetic | TFE | solution | Jirasko et al., Plos Pathogens | 2010 |
Hepatitis C virus (NS2) | Res 27-59 | a-helical transmembrane | 2KWT | 16886 | 4 kDa/1 | synthetic | TFE | solution | Jirasko et al., Plos Pathogens | 2010 |
Influenza hemagglutinin fusion peptide | - | Membrane associated proteins | 2KXA | 16907 | 3 kDa/1 | E. coli | DPC | solution | Lorieau et al., PNAS | 2010 |
Histidine kinase receptor QseC | Membrane domain | a-helical transmembrane | 2KSE | - | 21 kDa/1 | Cell Free Expression | LMPG | solution | Maslennikov et al, PNAS | 2010 |
Histidine kinase receptor ArcB | Membrane domain | a-helical transmembrane | 2KSD | - | 13 kDa/1 | Cell Free Expression | LMPG | solution | Maslennikov et al, PNAS | 2010 |
Histidine kinase receptor KdpD | Membrane domain | a-helical transmembrane | 2KSF | - | 11 kDa/1 | Cell Free Expression | LMPG | solution | Maslennikov et al, PNAS | 2010 |
Integrin beta3 subunit | - | a-helical transmembrane | 2KV9 | 16771 | 9 kDa/1 | E. coli | DPC | solution | Metcalf et al., PNAS | 2010 |
ErbB2 transmembrane segment | Transmembrane domain heterodimer of ErbB1 and ErbB2 | a-helical transmembrane | 2KS1 | - | 9 kDa/1 | E. coli | isotropic bicelles (140 mM DHPC; 35 mM DMPC; 40°C) | solution | Mineev et al., J. Mol. Biol. | 2010 |
Pf1 coat protein | - | a-helical transmembrane | 2KSJ | 5877 | 5 kDa/1 | Pseudomonas aeroginusa | DHPC, bicelles and lipids | solution and oriented | Park et al., Biophys. J. | 2010 |
Influenza M2 proton channel | Res 18-60 with rimantadine (BV27A mutant) | a-helical transmembrane | 2KWX | - | 18 kDa/4 | E. coli | DHPC (150 mM; 30°C) | solution | Pielak & Chou, Biochim. Biophys. Res. Commun. | 2010 |
Influenza M2 proton channel | Residues 22-62 | a-helical transmembrane | 2L0J | - | 20 kDa/4 | E. coli | lipids (DOPC, DOPC, 30°C) | oriented | Sharma et al., Science | 2010 |
NHE1 (Na(+)/H(+) exchanger isoform 1) | Transmembrane Segment VI | a-helical transmembrane | 2L0E | - | 3 kDa/1 | synthetic | DPC | solution | Tzeng et al., J. Biol. Chem. | 2010 |
Nogo (Neurite Outgrowth Inhibitor) | Nogo-66 | Membrane associated proteins | 2KO2 | 15933 | 9 kDa | E. coli | DPC | solution | Vasudevan et al., PNAS | 2010 |
CD4 | Transmembrane and cytoplasmic domains (from human CD4) | a-helical transmembrane | 2KLU | 15479 | 8 kDa/1 | E. coli | DPC | solution | Wittlich et al., Biochim Biophys. Acta | 2010 |
Hepatitis C virus | s34r envelope glycoprotein E2 | a-helical transmembrane | 2KZQ | 17011 | 4 kDa/1 | synthetic | TFE | solution | Albecka et al., J. Virol. | 2011 |
Mitochondrial uncoupling protein 2 | - | a-helical transmembrane | 2LCK | 17614 | 33 kDa/1 | E. coli | DPC, Cardiolipin, DMPC | solution | Berardi et al., Nature | 2011 |
OprH | From P. aeruginosa | Beta-barrels | 2LHF | 17842 | 20 kDa/1 | E. coli | DHPC | solution | Edrington et al., J. Biol. Chem. | 2011 |
Heparin binding antigen | C-terminal domain of Neisseria | Beta-barrels | 2LFU | 16679 | 21 kDa/1 | E. coli | DPC (30 mM) | solution | Esposito et al., J. Biol. Chem. | 2011 |
Ost4 | - | a-helical transmembrane | 2LAT | 17537 | 4 kDa/1 | synthetic | Chloroform/Methanol | solution | Gayen & Kang, Biochem. Biophys. Res. Commun. | 2011 |
Substance P | in isotropic q=0.25 DMPC/CHAPS/GM1 bicelles as a ligand for NK1R | Membrane associated proteins | 2KSB | 20117 | 1 kDa/1 | synthetic | isotropic bicelles | solution | Gayen et al., Biochim. Biophys. Acta. | 2011 |
Substance P | in water complexed with NK1R | Membrane associated proteins | 2KS9 | 20115 | 1 kDa/1 | synthetic | isotropic bicelles | solution | Gayen et al., Biochim. Biophys. Acta. | 2011 |
Substance P | in DMPC/CHAPS isotropic q=0.25 bicelles as a ligand for NK1R | Membrane associated proteins | 2KSA | 20116 | 1 kDa/1 | synthetic | isotropic bicelles | solution | Gayen et al., Biochim. Biophys. Acta. | 2011 |
Ebolavirus GP2 | pH 7.0 | Membrane associated proteins | 2LCZ | 17639 | 6 kDa/1 | E. coli | DPC (150mM) | solution | Gregory et al., PNAS | 2011 |
Ebolavirus GP2 | pH 5.5 | Membrane associated proteins | 2LCY | 17638 | 6 kDa/1 | E. coli | DPC (150mM) | solution | Gregory et al., PNAS | 2011 |
DsbB3 peptide | - | a-helical transmembrane | 2L0N | - | 4 kDa/1 | synthetic | 70% TFE | solution | Hwang and Hilty, Proteins | 2011 |
DsbB2 peptide | - | a-helical transmembrane | 2L0L | - | 3 kDa/1 | synthetic | TFE | solution | Hwang and Hilty, Proteins | 2011 |
DsbB3 peptide | - | a-helical transmembrane | 2L0O | - | 4 kDa/1 | synthetic | 100% TFE | solution | Hwang and Hilty, Proteins | 2011 |
DsbB2 peptide | - | a-helical transmembrane | 2L0M | - | 3 kDa/1 | synthetic | 100% TFE | solution | Hwang and Hilty, Proteins | 2011 |
ErbB3 | Dimeric transmembrane domain | Beta-barrels | 2L9U | 17488 | 9 kDa/2 | E. coli | DPC | solution | Mineev et al., Biochim. Biophys. Acta. | 2011 |
CCR5 | LC4 transmembrane segment | a-helical transmembrane | 2RRS | - | 2 kDa/1 | synthetic | SDS | solution | Miyamoto and Togiya, Plos One | 2011 |
Amylin | - | a-helical transmembrane | 2L86 | - | 4 kDa/1 | synthetic | SDS (200 mM) | solution | Nanga et al., Biochim. Biophys. Acta | 2011 |
Carnitine palmitoyltransferase 1A | N-terminal regulatory segment | Membrane associated proteins | 2LE3 | 17690 | 5 kDa/1 | E. coli | Various detergent micelles (DAC, DDAC, TDAC, HDAC, OM, DDMG...) | solution | Rao et al., J. Biol. Chem. | 2011 |
Proteorhodopsin | - | a-helical transmembrane | 2L6X | 17327 | 27 kDa/1 | Cell Free Expression | c7-DHPC | solution | Reckel et al., Angew. Chem. Int. Ed. Engl. | 2011 |
DsbB-DsbA | - | a-helical transmembrane | 2LEG | 17710 | 42 kDa/1 | E. coli (C43) | microcrystalised outside the lipid membrane with residual native lipids | MAS and X-ray | Tang et al., J. Biomol. NMR | 2011 |
Vasoactive intestinal peptide | - | Membrane associated proteins | 2RRH | 11419 | 3 kDa/1 | E. coli | Methanol | solution | Umetsu et al. Biochim. Biophys. Acta | 2011 |
Vasoactive intestinal peptide | - | Membrane associated proteins | 2RRI | 11420 | 3 kDa/1 | E. coli | DPC micelles | solution | Umetsu et al. Biochim. Biophys. Acta | 2011 |
AS1p-Tar peptide from HAMP domain | - | Membrane associated proteins | 2L9G | 17450 | 2 kDa/1 | synthetic | isotropic bicelles (240mM DHPC; 54mM DMPC; 6mM DMPG) | solution | Unnerstale et al., Biochim. Biophys. Acta | 2011 |
Phospholamban | - | a-helical transmembrane | 2KYV | - | 30 kDa/5 | E. coli | DPC (300 mM; 37°C) and lipids | solution, oriented and MAS | Verardi et al., PNAS | 2011 |
Amyloid precursor protein | C99 C-terminal fragment of the transmembrane domain (monomer) | a-helical transmembrane | 2LP1 | 15775 | 14 kDa/1 | E. coli | LMPG | solution | Barrett et al., Science | 2012 |
ErbB4 | Dimeric transmembrane domain | a-helical transmembrane | 2LCX | 7205 | 10 kDa/2 | E. coli | isotropic bicelles (67 mM DHPC, 15 mM DMPC) | solution | Bocharov et al., Biochim. Biophys. Acta. | 2012 |
Neuronal acetylcholine receptor M2 channel | Transmembrane domain alpha 4 subunit | a-helical transmembrane | 2LLY | 18093 | 15 kDa/1 | E. coli | LDAO | solution | Bondarenko et al., Biochim. Biophys. Acta | 2012 |
Neuronal acetylcholine receptor M2 channel | Transmembrane domain of the beta 2 subunit + a mutant | a-helical transmembrane | 2LM2 | 18096 | 15 kDa/1 | E. coli | isopropanol, Water (40°C) | solution | Bondarenko et al., Biochim. Biophys. Acta. | 2012 |
Mercury transporter Mer F | Integral membrane domain | a-helical transmembrane | 2LJ2 | 17914 | 6 kDa/1 | E. coli (C43) | DMPC | MAS | Das et al, JACS | 2012 |
HIGD1A | (PRE based backbone structure determination) | a-helical transmembrane | 2LOM | 18217 | 10 kDa/1 | Cell Free Expression | LMPG | solution | Klammt et al., Nat. Methods | 2012 |
TMEM141 | (PRE based backbone structure determination) | a-helical transmembrane | 2LOR | 18222 | 12 kDa/1 | Cell Free Expression | LMPG | solution | Klammt et al., Nat. Methods | 2012 |
HIGD1B | (PRE based backbone structure determination) | a-helical transmembrane | 2LON | 18218 | 11 kDa/1 | Cell Free Expression | LMPG | solution | Klammt et al., Nat. Methods | 2012 |
TMEM14A | (NOE based backbone structure determination) | a-helical transmembrane | 2LOO | 18219 | 12 kDa/1 | Cell Free Expression | LMPG | solution | Klammt et al., Nat. Methods | 2012 |
TMEM14A | (PRE based backbone structure determination) | a-helical transmembrane | 2LOP | 18220 | 12 kDa/1 | Cell Free Expression | LMPG | solution | Klammt et al., Nat. Methods | 2012 |
FAM14B (Interferon alpha-inducible protein 27-like protein 1) | - | a-helical transmembrane | 2LOQ | 18221 | 11 kDa/1 | Cell Free Expression | LMPG | solution | Klammt et al., Nat. Methods | 2012 |
TMEM14C | (PRE based backbone structure determination) | a-helical transmembrane | 2LOS | 18223 | 13 kDa/1 | Cell Free Expression | LMPG | solution | Klammt et al., Nat. Methods | 2012 |
Amyloid precursor protein | Small C-terminal fragment of the transmembrane domain | a-helical transmembrane | 2LOH | 18080 | 9 kDa/2 | E. coli | DPC | solution | Nadezhdin et al., FEBS Lett. | 2012 |
Hepatitis C virus core-E1 signal KKGF peptide | - | a-helical transmembrane | 2LIF | 16601 | 3 kDa/1 | synthetic | TFE | solution | Oehler et al., J. Virol. | 2012 |
Chemokine receptor CXCR1 | - | a-helical transmembrane | 2LNL | 18170 | 34 kDa/1 | E. coli | DMPC | MAS | Park et al., Nature | 2012 |
pepA1 | Apoptotic-like membrane peptide (from S. aureus ) | a-helical transmembrane | 4B19 | - | 3 kDa/1 | synthetic | Chloroform/Methanol | solution | Sayed et al., J. Biol. Chem. | 2012 |
YadA | Membrane anchor domain | Beta-barrels | 2LME | 18108 | 34 kDa/3 | E. coli | microcrystalised outside the lipid membrane | MAS | Shahid et al., Nat. Methods | 2012 |
Rabbit cytochrome b5 | - | a-helical transmembrane | 2M33 | 18919 | 13 kDa/1 | E. coli | DPC and bicelles | solution and oriented | Ahuja et al., J. Biol. Chem. | 2013 |
FGFR3 | Transmembrane domain dimer | a-helical transmembrane | 2LZL | 18763 | 9 kDa/2 | E. coli | DPC (88 mM) and SDS (10 mM) | solution | Bocharov et al. Structure | 2013 |
OmpX | in nanodiscs | Beta-barrels | 2M06 | 18796 | 16 kDa/1 | E. coli | nanodiscs (DMPC/DMPG:3/1 | solution | Hagn et al., JACS | 2013 |
OmpX | in micelles | Beta-barrels | 2M07 | 18797 | 16 kDa/1 | E. coli | DPC (110mM) | solution | Hagn et al., JACS | 2013 |
t-SNARE Syntaxin-1A | - | a-helical transmembrane | 2M8R | 19266 | 12 kDa/1 | E. coli | DPC (100 mM; 40°C) | solution | Liang et al., PNAS | 2013 |
Mercury transporter Mer F | - | a-helical transmembrane | 2M67 | 19115 | 9 kDa/1 | E. coli (C41) | DMPC | oriented and MAS | Lu et al., JACS | 2013 |
Htt17 of Huntingtin | N-terminal domain | Membrane associated proteins | 2LD0 | 17642 | 2 kDa/1 | synthetic | 50% TFE | solution | Michalek et al., Biochemistry | 2013 |
Htt17 of Huntingtin | N-terminal domain | Membrane associated proteins | 2LD2 | 17644 | 2 kDa/1 | synthetic | DPC micelles | oriented and solution | Michalek et al., Biochemistry | 2013 |
Glycine receptor alpha1 | Pentameric open-channel | a-helical transmembrane | 2M6I | 19126 | 87 kDa/5 | E. coli | LPPG (100 mM) | solution | Mowrey et al., Structure | 2013 |
Glycine receptor alpha1 | Full length transmembrane domain, monomer | a-helical transmembrane | 2M6B | 19126 | 17 kDa/1 | E. coli | LPPG (100 mM) | solution | Mowrey et al., Structure | 2013 |
Hepatitis C virus (p7 channel) | - | a-helical transmembrane | 2M6X | 19162 | 41 kDa/6 | E. coli | DPC (200 mM) | solution | OuYang et al., Nature | 2013 |
Temporin-1 Ta | - | a-helical transmembrane | 2MAA | 19334 | 1 kDa/1 | E. coli | LPS | solution | Saravanan et al., PLoS One | 2013 |
Antiamoebin I | - | Membrane associated proteins | 2M1F | 4993 | 2 kDa/1 | synthetic | isotropic bicelles (30mM DMPC; 120mM DHPC) | solution | Shenkarev et al., Chem. Biodivers. | 2013 |
Phospholamban | Monomeric human phospholamban in the R state. Mutant C36A, C41F, C46A | a-helical transmembrane | 2LPF | 18256 | 6 kDa/1 | E. coli | DPC (100 mM) | solution | Simone et al. , Biochemistry | 2013 |
DsbB | C41S mutant | a-helical transmembrane | 2LTQ | 18493 | 18 kDa/1 | E. coli (C43) | microcrystalised outside the lipid membrane with residual native lipids | MAS and X-ray | Tang et al., J. Mol. Biol. | 2013 |
Sod2 | Transmembrane Segment IV of the salt tolerance protein Sod2 | a-helical transmembrane | 2M7X | 19216 | 3 kDa/1 | E. coli | Chloroform/Propanol | solution | Ullah et al., J. Biol. Chem. | 2013 |
Phospholamban | Phosphorylated | a-helical transmembrane | 2M3B | 18952 | 31 kDa/5 | E. coli | DPC and DOPC/DOPE | solution, oriented and MAS | Vostrikov et al., Structure | 2013 |
tBid and its BH3 domain | - | Membrane associated proteins | 2M5I | 19054 | 15 kDa/1 | E. coli | LPPG | solution | Wang and Tjandra, J. Biol. Chem. | 2013 |
Anabaena Sensory Rhodopsin | - | a-helical transmembrane | 2M3G | 18595 | 83 kDa/3 | E. coli | lipids (DMPC/DMPA:9/1) | MAS | Wang et al., Nat. Methods | 2013 |
Neuronal acetylcholine receptor M2 channel | Transmembrane domain of the alpha 7 subunit | a-helical transmembrane | 2MAW | 19379 | 15 kDa/1 | E. coli | LDAO | solution | Mowrey et al, J. Biol. Chem. | 2014 |
GB virus B (NS2) | Res 2-32 | a-helical transmembrane | 2LZP | 18768 | 3 kDa/1 | synthetic | TFE/H2O | solution | Boukadida et al. J. Virol. | 2014 |
GB virus B (NS2) | Res 32-57 | a-helical transmembrane | 2LZQ | 18769 | 3 kDa/1 | synthetic | TFE/H2O | solution | Boukadida et al. J. Virol. | 2014 |
GB virus B (NS2) | Res 113-137 | a-helical transmembrane | 2MKB | 19765 | 3 kDa/1 | synthetic | TFE/H2O | solution | Boukadida et al. J. Virol. | 2014 |
Amyloid precursor protein | Transmembrane domain of the amyloid beta A4 precursor protein (V44M mutant) | a-helical transmembrane | 2LZ4 | 18648 | 6 kDa/2 | E. coli | DPC | solution | Chen et al., Nat. Comm. | 2014 |
Amyloid precursor protein | Transmembrane domain of the amyloid beta A4 precursor protein | a-helical transmembrane | 2LZ3 | 18649 | 6 kDa/2 | E. coli | DPC | solution | Chen et al., Nat. Comm. | 2014 |
LpoB (Outer-membrane lipoprotein ) | - | Membrane associated proteins | 2MII | 19681 | 21 kDa/1 | E. coli | sodium acetate | solution | Egan et al., PNAS | 2014 |
YgaP | - | a-helical transmembrane | 2MPN | 19994 | 14 kDa/2 | E. coli | solution | Eichmann et al., J. Biol. Chem. | 2014 | |
VP7 rotavirus outer capsid protein | C-terminal domain | a-helical transmembrane | 2LM7 | - | 7 kDa/1 | synthetic | DPC (100 mM) | solution | Elaid et al., Biochim. Biophys. Acta | 2014 |
VP7 rotavirus outer capsid protein | C-terminal domain | a-helical transmembrane | 2KVL | - | 7 kDa/1 | synthetic | Chloroform/Methanol | solution | Elaid et al., Biochim. Biophys. Acta. | 2014 |
Chemokine receptor CCR2 | Membrane-proximal C-terminal region | a-helical transmembrane | 2MLQ | 19828 | 2 kDa/1 | E. coli (C41) | 8uM FROUNT | solution | Esaki et al. FEBS J. | 2014 |
Chemokine receptor CCR2 | Membrane-proximal C-terminal region | a-helical transmembrane | 2MLO | 19828 | 2 kDa/1 | E. coli (C41) | 10mM DPC | solution | Esaki et al. FEBS J. | 2014 |
Opacity protein opA60 | - | Beta-barrels | 2MAF | 19343 | 27 kDa/1 | E. coli | - | solution | Fox et al. , JACS | 2014 |
Opacity protein opA60 | in FC-12 Micelles | Beta-barrels | 2MLH | 19343 | 27 kDa/1 | E. coli | - | solution | Fox et al., JACS | 2014 |
Ebolavirus GP2 | pH 5.5, mutant L529A/I544A | Membrane associated proteins | 2M5F | 19052 | 6 kDa/1 | E. coli | DPC (150mM) | solution | Gregory et al., J. Virol. | 2014 |
Ebolavirus GP2 | pH 5.5, mutant I544A | Membrane associated proteins | 2MB1 | 19383 | 6 kDa/1 | E. coli | DPC (150mM) | solution | Gregory et al., J. Virol. | 2014 |
OmpW | - | Beta-barrels | 2MHL | 19637 | 21 kDa/1 | E. coli | 30-Fos | solution | Horst et al., Structure | 2014 |
OmpA | Periplasmic domain | Beta-barrels | 2MQE | 25030 | 16 kDa/1 | E. coli | sodium phosphate | solution | Ishida et al., Biochim. Biophys. Acta | 2014 |
LpoA (outer-membrane lipoprotein ) | - | Membrane associated proteins | 2MHK | 18853 | 28 kDa/1 | E. coli | sodium acetate | solution | Jean et al., Structure | 2014 |
MgtR (Salmonella transmembrane regulatory peptide) | - | a-helical transmembrane | 2MC7 | 19334 | 3 kDa/1 | Synthetic | DMPC (37°C) | oriented | Jean-François et al., J. Mol. Biol. | 2014 |
Zn2+-transporting four-helix bundle | Transmembrane domain | a-helical transmembrane | 2MUZ | 25236 | 12 kDa/4 | synthetic | MAS | Joh et al., Science | 2014 | |
SARS Coronavirus envelope (CoV E) | Channel-forming α-helical TM domain of the | a-helical transmembrane | 2MM4 | 19845 | 6 kDa/1 | E. coli | SDS | solution | Li et al. J. Biol. Chem. | 2014 |
Insulin receptor | Transmembrane domain | a-helical transmembrane | 2MFR | 19568 | 7 kDa/1 | E. coli | DPC | solution | Li et al., Biochim. Biophys. Acta. | 2014 |
Erythropoietin Receptor | - | a-helical transmembrane | 2MV6 | 25079 | 5 kDa/1 | E. coli | DPC | solution | Li et al., Biophys. J. | 2014 |
VEGFR2 receptor | Trimer | a-helical transmembrane | 2MET | 19531 | 12 kDa/3 | E. coli | solution | Manni et al., Structure | 2014 | |
VEGFR2 receptor | Dimer | a-helical transmembrane | 2MEU | 19532 | 8 kDa/2 | E. coli | solution | Manni et al., Structure | 2014 | |
Lasiocepsin | - | a-helical transmembrane | 2MBD | 19396 | 3 kDa/1 | Synthetic | SDS (100 mM) | solution | Monincova et al., Chembiochem | 2014 |
Piscidin-3 | - | a-helical transmembrane | 2MCX | 19457 | 2 kDa/1 | synthetic | POPE/POPG bilayer (22°C) | oriented | Perrin et al., JACS | 2014 |
Piscidin-3 | - | a-helical transmembrane | 2MCW | 19456 | 2 kDa/1 | synthetic | DMPC/DMPG bilayer (40°C) | oriented | Perrin et al., JACS | 2014 |
Piscidin 1 | - | a-helical transmembrane | 2MCU | 19454 | 3 kDa/1 | synthetic | DMPC/DMPG bilayer (40°C) | oriented | Perrin et al., JACS | 2014 |
Piscidin 1 | - | a-helical transmembrane | 2MCV | 19455 | 3 kDa/1 | synthetic | POPE/POPG bilayer (22°C) | oriented | Perrin et al., JACS | 2014 |
HIV gp41 | MPER trimer | a-helical transmembrane | 2LP7 & 2M7W | 18237 | 21 kDa/3 | E. coli | DPC (100 mM) | solution | Reardon et al., PNAS | 2014 |
HIV gp41 | Ectodomain | a-helical transmembrane | MK32 | 19750 | 8 kDa/1 | E. coli | DPC (100 mM) | solution | Roche et al., PNAS | 2014 |
LAMP-2A (Lysosome-Associated Membrane Protein Type 2a) | Transmembrane Domain, oligomer | a-helical transmembrane | 2 | 19941 | 13 kDa/3 | E. coli | 150mM DPC + 5mM DMPC | solution | Rout et al., J. Biol. Chem. | 2014 |
LAMP-2A (Lysosome-Associated Membrane Protein Type 2a) | Transmembrane Domain, monomer | a-helical transmembrane | 2MOF | 19941 | 4 kDa/1 | E. coli | 150mM DPC + 5mM DMPC | solution | Rout et al., J. Biol. Chem. | 2014 |
Mercury transporter Mer F | Full length | a-helical transmembrane | 2MOZ | 19115 | 9 kDa/1 | E. coli (C41) | bicelles and DMPC | oriented and MAS | Tian et al., J. Biomol. NMR | 2014 |
Protegrin-2 | - | a-helical transmembrane | 2MUH | 25212 | 2 kDa/1 | synthetic | DPC | solution | Usachev et al., J. Biomol. NMR | 2014 |
Influenza A virus M2 | N31S mutant, ses 19-49 bound to drug 11 | a-helical transmembrane | 2MUW | 25234 | 14 kDa/4 | solution | Wu et al., JACS | 2014 | ||
Influenza A virus M2 | Res 19-49 bound to drug 11 | a-helical transmembrane | 2MUV | 25233 | 14 kDa/4 | solution | Wu et al., JACS | 2014 | ||
TatB component of the twin-arginine translocation system | - | a-helical transmembrane | 2MI2 | 19618 | 12 kDa/1 | E. coli | DPC (40 mM) | solution | Zhang et al., Biochim. Biophys. Acta | 2014 |
Influenza M2 proton channel | Res 18-60 construct of the S31N mutant | a-helical transmembrane | 2N70 | 25788 | 20 kDa/4 | E. coli | MAS | Andreas et al., JACS | 2015 | |
OmpX | by residual dipolar couplings in nanodiscs | Beta-barrels | 2MNH | 19892 | 16 kDa/1 | E. coli | in MSPdeltaH5 nanodiscs | solution | Bibow et al., Protein Sci. | 2015 |
CrgA | a-helical transmembrane | 2MMU | 19867 | 12 kDa/1 | E. coli | oriented | Das et al., PNAS | 2015 | ||
FXYD2b | - | a-helical transmembrane | 2MKV | - | 7 kDa/1 | E. coli | SDS (500 mM) or DPC (150 mM) | solution | Gong et al. Biochim. Biophys. Acta | 2015 |
TSPO (mitochondrial translocator protein) in complex with pk11195 | A147T mutant | a-helical transmembrane | 2N02 | 25513 | 19 kDa/1 | E. coli | solution | Jaremko et al., Chembiochem | 2015 | |
OprG | from Pseudomonas aeruginosa | Beta-barrels | 2N6L | 25768 | 24 kDa/1 | E. coli | DHPC micelles | solution | Kucharska et al., Structure | 2015 |
OprG | from Pseudomonas aeruginosa, mutant P92A | Beta-barrels | 2N6P | 25776 | 24 kDa/1 | E. coli | DHPC micelles | solution | Kucharska et al., Structure | 2015 |
SARS-CoV | Spike Glycoprotein of SARS Coronavirus fragments (Fusion peptide) | a-helical transmembrane | 2RUM | - | 2 kDa/1 | synthetic | 125mM DPC | solution | Mahajan & Bhattacharjya, Biochim. Biophys. Acta. | 2015 |
SARS-CoV | Spike Glycoprotein of SARS Coronavirus fragments (Fusion Peptide) | a-helical transmembrane | 2RUN | - | 2 kDa/1 | synthetic | 125mM DPC | solution | Mahajan and Bhattacharjya, Biochim. Biophys. Acta | 2015 |
SARS-CoV | Spike Glycoprotein of SARS Coronavirus fragments (Internal fusion Peptide) | a-helical transmembrane | 2RUO | - | 2 kDa/1 | synthetic | 125mM DPC | solution | Mahajan et al., Biochim. Biophys. Acta | 2015 |
Ail (attachment invasion locus) | - | Beta-barrels | 2N2M | 25281 | 17 kDa/1 | E. coli | DePC micelles | solution | Marassi et al., J. Biomol. NMR | 2015 |
Ail (attachment invasion locus) | Calculated with implicit membrane solvation | Beta-barrels | 2N2L | 25281 | 17 kDa/1 | E. coli | DePC micelles | solution | Marassi et al., J. Biomol. NMR | 2015 |
CcdA (electron Transporter) | - | a-helical transmembrane | 2N4X | 25685 | 23 kDa/1 | E. coli | solution | Williamson et al., Nat. Struct. Mol. Biol. | 2015 | |
HER2/ErbB2 | - | a-helical transmembrane | 2N2A | 25593 | 13 kDa/2 | E. coli | solution | Bragin et al., J. Mol. Biol. | 2016 | |
HIV-1 gp41 | Trimer | a-helical transmembrane | 5JYN | 30090 | 14 kDa/3 | E. coli | solution | Dev et al., Science | 2016 | |
VDAC-1 | E73V mutant | Beta-barrels | 5JDP | 30065 | 31 kDa/1 | E. coli | 2% LDAO micelle | solution | Jaremko et al., Angew. Chem. Int. Ed. Engl. | 2016 |
Nicastrin | Transmembrane domain | a-helical transmembrane | 2N7Q | 25817 | 6 kDa/1 | E. coli | SDS micelles | solution | Li et al., Sci. Rep. | 2016 |
Nicastrin | Transmembrane domain | a-helical transmembrane | 2N7R | 25818 | 6 kDa/1 | E. coli | DPC micelles | solution | Li et al., Sci. Rep. | 2016 |
EcDsbA-sulfonamide1 complex | - | a-helical transmembrane | 2NDO | 19664 | 22 kDa/1 | E. coli | solution | Mohanty et al., J. Biomol. NMR | 2016 | |
p75 neurotrophin receptor | C257A mutant | a-helical transmembrane | 2MJO | 19741 | 9 kDa/2 | E. coli | DPC micelles | solution | Nadezhdin et al., J. Biol. Chem. | 2016 |
p75 neurotrophin receptor | - | a-helical transmembrane | 2MIC | 19673 | 9 kDa/2 | E. coli | DPC micelles | solution | Nadezhdin et al., J. Biol. Chem. | 2016 |
Mitochondrial Calcium Uniporter (MCU) | Pore-forming region | a-helical transmembrane | 5ID3 | 30021 | 95 kDa/5 | E. coli | solution | Oxenoid et al., Nature | 2016 | |
EGFR | - | a-helical transmembrane | 5LV6 | 34040 | 9 kDa/1 | E. coli | solution | Bocharov et al., Biochemistry | 2017 | |
Scavenger receptor BI (SR-BI) | Transmembrane domain | a-helical transmembrane | 5KTF | 30137 | 8 kDa/1 | E. coli | solution | Chadwick et al., Structure | 2017 | |
Ail (outer membrane protein) | from Yersinia pestis | Beta-barrels | 5VJ8 | 30284 | 17 kDa/1 | E. coli | - | solution | Dutta et al., to be published | 2017 |
HER2 | Transmembrane domain | a-helical transmembrane | 2OB4 | 34154 | 9 kDa/1 | E. coli (DE3) | in DPC micelles | solution | Lesovoy et al., J. Biomol. NMR | 2017 |
Anabaena Sensory Rhodopsin | - | a-helical transmembrane | 2UK6 | - | 83 kDa/3 | E. coli | MAS | Milikisiyants et al., J. Mol. Biol. | 2017 | |
Dermcidin | - | a-helical transmembrane | 2NDK | 26063 | 5 kDa/1 | E. coli | solution | Nguyen et al., Sci. Rep. | 2017 | |
OmpG | - | Beta-barrels | 5MWV | 34088 | 33 kDa/1 | E. coli | E. coli lipid extracts | MAS | Retel et al., Nat. Comm. | 2017 |
HIV-1 gp41 | Transmembrane domain | a-helical transmembrane | 6B3U | 30349 | 5 kDa/1 | E. coli | Bicelles | solution | Chiliveri et al., JACS | 2018 |
CcdA (electron transporter) | - | a-helical transmembrane | 5VKV | 30286 | 25 kDa/1 | E. coli | solution | Zhou et al., NSMB | 2018 | |
Rcf1 | Dimer | a-helical transmembrane | 5NF8 | 34115 | 41 kDa/2 | E. coli | DPC micelles | solution | Zhou et al., PNAS | 2018 |
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