2024
129. Magic-angle spinning NMR spectral editing of polysaccharides in whole cells using the DREAM scheme.
Delcourte L, Berbon M, Rodriguez M, Subban K, Lends A, Grélard A, Morvan E, Habenstein B, Saupe SJ, Delhaes L, Aimanianda V, Daskalov A, Loquet A.
Methods. 2024 Jul 22;230:59-67. doi: 10.1016/j.ymeth.2024.07.003
128. Integrating Mechanics and Bioactivity: A Detailed Assessment of Elasticity and Viscoelasticity at Different Scales in 2D Biofunctionalized PEGDA Hydrogels for Targeted Bone Regeneration.
López-Serrano C, Côté-Paradis Y, Habenstein B, Loquet A, Le Coz C, Ruel J, Laroche G, Durrieu MC.
ACS Appl Mater Interfaces. 2024 Jul 31;16(30):39165-39180. doi: 10.1021/acsami.4c10755
127. Two Paenibacillus spp. strains promote grapevine wood degradation by the fungus Fomitiporia mediterranea: from degradation experiments to genome analyses.
Haidar R, Compant S, Robert C, Antonielli L, Yacoub A, Grélard A, Loquet A, Brader G, Guyoneaud R, Attard E, Rey P.
Sci Rep. 2024 Jul 9;14(1):15779. doi: 10.1038/s41598-024-66620-x.
126. NMR resonance assignment of the cell death execution domain BELL2 from multicellular bacterial signalosomes.
Delcourte L, Sanchez C, Morvan E, Berbon M, Grélard A, Saragaglia C, Dakhli T, Thore S, Bardiaux B, Habenstein B, Kauffmann B, Saupe SJ, Loquet A.
Biomol NMR Assign. 2024 Jun 22. doi: 10.1007/s12104-024-10183-5.
125. A Targetable N-Terminal Motif Orchestrates α-Synuclein Oligomer-to-Fibril Conversion.
Santos J, Cuellar J, Pallarès I, Byrd EJ, Lends A, Moro F, Abdul-Shukkoor MB, Pujols J, Velasco-Carneros L, Sobott F, Otzen DE, Calabrese AN, Muga A, Pedersen JS, Loquet A, Valpuesta JM, Radford SE, Ventura S.
J Am Chem Soc. 2024 May 8;146(18):12702-12711. doi: 10.1021/jacs.4c02262.
124. Analytical Framework to Understand the Origins of Methyl Side-Chain Dynamics in Protein Assemblies.
Zumpfe K, Berbon M, Habenstein B, Loquet A, Smith AA.
J Am Chem Soc. 2024 Mar 27;146(12):8164-8178. doi: 10.1021/jacs.3c12620.
123. Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils.
Sharma K, Stockert F, Shenoy J, Berbon M, Abdul-Shukkoor MB, Habenstein B, Loquet A, Schmidt M, Fändrich M.
Nature Communication 2024 Jan 12;15(1):486. doi: 10.1038/s41467-023-44489-0.
2023
122. Molecular characterization of the N-terminal half of TasA during amyloid-like assembly and its contribution to Bacillus subtilis biofilm formation.
Cámara-Almirón J, Domínguez-García L, El Mammeri N, Lends A, Habenstein B, de Vicente A, Loquet A, Romero D.
NPJ Biofilms Microbiomes. 2023 Sep 22;9(1):68. doi: 10.1038/s41522-023-00437-w.
121. Efficient 18.8 T MAS-DNP NMR reveals hidden side chains in amyloid fibrils.
Lends A, Birlirakis N, Cai X, Daskalov A, Shenoy J, Abdul-Shukkoor MB, Berbon M, Ferrage F, Liu Y, Loquet A, Tan KO.
J Biomol NMR. 2023 Jun;77(3):121-130. doi: 10.1007/s10858-023-00416-5.
120. Structural polymorphism of the low-complexity C-terminal domain of TDP-43 amyloid aggregates revealed by solid-state NMR.
Shenoy J, Lends A, Berbon M, Bilal M, El Mammeri N, Bertoni M, Saad A, Morvan E, Grélard A, Lecomte S, Theillet FX, Buell AK, Kauffmann B, Habenstein B, Loquet A.
Front Mol Biosci. 2023 Mar 29;10:1148302. doi: 10.3389/fmolb.2023.1148302
119. Switchable Lipids: From Conformational Switch to Macroscopic Changes in Lipid Vesicles.
Phan HT, Passos Gibson V, Guédin A, Ibarboure E, El Mammeri N, Grélard A, Le Meins JF, Dufourc EJ, Loquet A, Giasson S, Leblond Chain J.
Langmuir. 2023 Feb 15. doi: 10.1021/acs.langmuir.2c03149.
118. Dynamic Sorting of Mobile and Rigid Molecules in Biomembranes by Magic-Angle Spinning 13C NMR.
Morvan E, Taib-Maamar N, Grélard A, Loquet A, Dufourc EJ.
Anal Chem. 2023 Feb 7. doi: 10.1021/acs.analchem.2c04185.
117. The rigid core and flexible surface of amyloid fibrils probed by Magic-Angle Spinning NMR of aromatic residues.
Becker LM, Berbon M, Vallet A, Grelard A, Morvan E, Bardiaux B, Lichtenecker R, Ernst M, Loquet A, Schanda P.
Angew Chem Int Ed Engl. 2023 Feb 4. doi: 10.1002/anie.202219314.
116. Solid-state NMR molecular snapshots of Aspergillus fumigatus cell wall architecture during a conidial morphotype transition.
Lamon G, Lends A, Valsecchi I, Wong SSW, Duprès V, Lafont F, Tolchard J, Schmitt C, Mallet A, Grélard A, Morvan E, Dufourc EJ, Habenstein B, Guijarro JI, Aimanianda V, Loquet A.
Proc Natl Acad Sci U S A. 2023 Feb 7;120(6):e2212003120. doi: 10.1073/pnas.2212003120.
115. Evidence for [2Fe-2S]2+ and Linear [3Fe-4S]1+ Clusters in a Unique Family of Glycine/Cysteine-Rich Fe-S Proteins from Megavirinae Giant Viruses
Villalta A, Srour B, Lartigue A, Clémancey M, Byrne D, Chaspoul F, Loquet A, Guigliarelli B, Blondin G, Abergel C, Burlat B.
J Am Chem Soc. 2023 Jan 27. doi: 10.1021/jacs.2c10484.
114. The Pga59 cell wall protein is an amyloid forming protein involved in adhesion and biofilm establishment in the pathogenic yeast Candida albicans
Mourer T, El Ghalid M, Pehau-Arnaudet G, Kauffmann B, Loquet A, Brûlé S, Cabral V, d’Enfert C, Bachellier-Bassi S.
NPJ Biofilms Microbiomes. 2023 Jan 25;9(1):6. doi: 10.1038/s41522-023-00371-x
113. Supramolecular organization and dynamics of mannosylated phosphatidylinositol lipids in the mycobacterial plasma membrane.
Brown CM, Corey RA, Grélard A, Gao Y, Choi YK, Luna E, Gilleron M, Destainville N, Nigou J, Loquet A, Fullam E, Im W, Stansfeld PJ, Chavent M.
Proc Natl Acad Sci U S A. 2023 Jan 31;120(5):e2212755120. doi: 10.1073/pnas.2212755120
2022
112. Unraveling Membrane Perturbations Caused by the Bacterial Riboregulator Hfq.
Turbant F, Waeytens J, Campidelli C, Bombled M, Martinez D, Grélard A, Habenstein B, Raussens V, Velez M, Wien F, Arluison V.
Int J Mol Sci. 2022 Aug 5;23(15):8739. doi: 10.3390/ijms23158739
111. Structural determinants of REMORIN nanodomain formation in anionic membranes.
Legrand A, G-Cava D, Jolivet MD, Decossas M, Lambert O, Bayle V, Jaillais Y, Loquet A, Germain V, Boudsocq M, Habenstein B, Vélez Tirado M, Mongrand S.
Biophys J. 2022 Dec 28:S0006-3495(22)03964-9. doi: 10.1016/j.bpj.2022.12.035
110. Bio-membranes: Picosecond to second dynamics and plasticity as deciphered by solid state NMR.
Morvan E, Taib-Maamar N, Grélard A, Loquet A, Dufourc EJ.
Biochim Biophys Acta Biomembr. 2022 Nov 25:184097. doi: 10.1016/j.bbamem.2022.184097.
109. Cell-free synthesis of amyloid fibrils with infectious properties and amenable to sub-milligram magic-angle spinning NMR analysis.
Lends A, Daskalov A, Maleckis A, Delamare A, Berbon M, Grélard A, Morvan E, Shenoy J, Dutour A, Tolchard J, Noubhani A, Giraud MF, Sanchez C, Habenstein B, Guichard G, Compain G, Jaudzems K, Saupe SJ, Loquet A.
Commun Biol. 2022 Nov 9;5(1):1202. doi: 10.1038/s42003-022-04175-1.
108. Neurons with Cat’s Eyes: A Synthetic Strain of α-Synuclein Fibrils Seeding Neuronal Intranuclear Inclusions.
De Giorgi F, Abdul-Shukkoor MB, Kashyrina M, Largitte LA, De Nuccio F, Kauffmann B, Lends A, Laferrière F, Bonhommeau S, Lofrumento DD, Bousset L, Bezard E, Buffeteau T, Loquet A, Ichas F.
Biomolecules. 2022 Mar 11;12(3):436. doi: 10.3390/biom12030436.
107. Methoxpropamine (MXPr) in powder, urine and hair samples: Analytical characterization and metabolite identification of a new threat..
Goncalves R, Castaing N, Richeval C, Ducint D, Titier K, Morvan E, Grélard A, Loquet A, Molimard M.
Forensic Sci Int. 2022 pr;333:111215. doi: 10.1016/j.forsciint.2022.111215.
2021
106. Protein resonance assignment by solid-state NMR based on 1H-detected 13C double-quantum spectroscopy at fast MAS.
Lends A, Berbon M, Habenstein B, Nishiyama Y, Loquet A.
J Biomol NMR. 2021 Nov 23. doi: 10.1007/s10858-021-00386-6.
105. Connecting the dots: from nanodomains to physiological functions of REMORINs.
Gouguet P, Gronnier J, Legrand A, Perraki A, Jolivet MD, Deroubaix AF, German-Retana S, Boudsocq M, Habenstein B, Mongrand S, Germain V.
Plant Physiol. 2021 Apr 2;185(3):632-649. doi: 10.1093/plphys/kiaa063.
104. Bacteria associated with wood tissues of Esca-diseased grapevines: functional diversity and synergy with Fomitiporia mediterranea to degrade wood components.
Haidar R, Yacoub A, Vallance J, Compant S, Antonielli L, Saad A, Habenstein B, Kauffmann B, Grélard A, Loquet A, Attard E, Guyoneaud R, Rey P.
Environ Microbiol. 2021 Oct;23(10):6104-6121. doi: 10.1111/1462-2920.15676.
103. Structures of Pathological and Functional Amyloids and Prions, a Solid-State NMR Perspective.
Daskalov A, El Mammeri N, Lends A, Shenoy J, Lamon G, Fichou Y, Saad A, Martinez D, Morvan E, Berbon M, Grélard A, Kauffmann B, Ferber M, Bardiaux B, Habenstein B, Saupe SJ, Loquet A.
Front Mol Neurosci. 2021 Jul 1;14:670513. doi: 10.3389/fnmol.2021.670513.
102. Bolaamphiphile-based supramolecular gels with drugs eliciting membrane effects.
Latxague L, Benizri S, Gaubert A, Tolchard J, Martinez D, Morvan E, Grélard A, Saad A, Habenstein B, Loquet A, Barthélémy P.
J Colloid Interface Sci. 2021 Mar 15;594:857-863. doi: 10.1016/j.jcis.2021.03.026.
101. New Insights into Wine Taste: Impact of Dietary Lipids on Sensory Perceptions of Grape Tannins.
Saad A, Bousquet J, Fernandez-Castro N, Loquet A, Géan J.
J Agric Food Chem. 2021 Mar 17;69(10):3165-3174. doi: 10.1021/acs.jafc.0c06589.
100. Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer’s Disease, Parkinson’s Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis.
Nguyen PH, Ramamoorthy A, Sahoo BR, Zheng J, Faller P, Straub JE, Dominguez L, Shea JE, Dokholyan NV, De Simone A, Ma B, Nussinov R, Najafi S, Ngo ST, Loquet A, Chiricotto M, Ganguly P, McCarty J, Li MS, Hall C, Wang Y, Miller Y, Melchionna S, Habenstein B, Timr S, Chen J, Hnath B, Strodel B, Kayed R, Lesné S, Wei G, Sterpone F, Doig AJ, Derreumaux P.
Chem Rev. 2021 Feb 24;121(4):2545-2647. doi: 10.1021/acs.chemrev.0c01122.
99. Structural and molecular basis of cross-seeding barriers in amyloids.
A. Daskalov, D. Martinez, V. Coustou, N. El Mammeri, M. Berbon, L.B. Andreas, B. Bardiaux, J. Stanek, A. Noubhani, B. Kauffmann, J.S. Wall, G. Pintacuda, S.J. Saupe, B. Habenstein, A. Loquet
Proc Natl Acad Sci U S A., 2021, Jan 5;118(1):e2014085118. doi: 10.1073/pnas.2014085118.
2020
98. Identification of NLR-associated amyloid signaling motifs in bacterial genomes.
Dyrka W, Coustou V, Daskalov A, Lends A, Bardin T, Berbon M, Kauffmann B, Blancard C, Salin B, Loquet A, Saupe SJ.
J Mol Biol. 2020 Oct 12:S0022-2836(20)30580-5. doi: 10.1016/j.jmb.2020.10.004.
97. Novel self-replicating α-synuclein polymorphs that escape ThT monitoring can spontaneously emerge and acutely spread in neurons.
De Giorgi F, Laferrière F, Zinghirino F, Faggiani E, Lends A, Bertoni M, Yu X, Grélard A, Morvan E, Habenstein B, Dutheil N, Doudnikoff E, Daniel J, Claverol S, Qin C, Loquet A, Bezard E, Ichas F.
Science Advances 2020 Oct 2;6(40):eabc4364. doi: 10.1126/sciadv.abc4364.
96. Tandem NMR and mass spectrometry analysis of human nuclear membrane lipids.
Dazzoni R, Buré C, Morvan E, Grélard A, Gounou C, Schmitter JM, Loquet A, Larijani B, Dufourc EJ.
Anal Chem. 2020 Apr 23. doi: 10.1021/acs.analchem.9b05052.
95. The unprecedented membrane deformation of the human nuclear envelope, in a magnetic field, indicates formation of nuclear membrane invaginations.
Dazzoni R, Grélard A, Morvan E, Bouter A, Applebee C, Loquet A, Larijani B, Dufourc E.
Sci. Rep. 2020 in press
94. Structures of Type III Secretion System Needle Filaments.
Habenstein B, El Mammeri N, Tolchard J, Lamon G, Tawani A, Berbon M, Loquet A.
Curr Top Microbiol Immunol. 2020 Jan 24. doi: 10.1007/82_2019_192.
93. MRI assessment of multiple dipolar relaxation time (T1D) components in biological tissues interpreted with a generalized inhomogeneous magnetization transfer (ihMT) model.
Carvalho VND, Hertanu A, Grélard A, Mchinda S, Soustelle L, Loquet A, Dufourc EJ, Varma G, Alsop DC, Thureau P, Girard OM, Duhamel G.
J Magn Reson. 2020 Feb;311:106668. doi: 10.1016/j.jmr.2019.106668.
2019
92. Sensitivity boosts by the CPMAS CryoProbe for challenging biological assemblies.
Hassan A, Quinn CM, Struppe J, Sergeyev IV, Zhang C, Guo C, Runge B, Theint T, Dao HH, Jaroniec CP, Berbon M, Lends A, Habenstein B, Loquet A, Kuemmerle R, Perrone B, Gronenborn AM, Polenova T.
J Magn Reson. 2019 Dec 23;311:106680. doi: 10.1016/j.jmr.2019.106680.
91. Structural dissection of amyloid aggregates of TDP-43 and its C-terminal fragments TDP-35 and TDP-16.
Shenoy K P J, El Mammeri N, Dutour A, Berbon M, Saad A, Lends A, Morvan E, Grélard A, Lecomte S, Kauffmann B, Theillet FX, Habenstein B, Loquet A.
FEBS J. 2019 Nov 29. doi: 10.1111/febs.15159.
90. Nanodomain Clustering of the Plant Protein Remorin by Solid-State NMR.
Legrand A, Martinez D, Grélard A, Berbon M, Morvan E, Tawani A, Loquet A, Mongrand S, Habenstein B.
Front Mol Biosci. 2019 Oct 15;6:107. doi: 10.3389/fmolb.2019.00107.
89. Mechanisms governing subcompartmentalization of biological membranes.
Gronnier J, Legrand A, Loquet A, Habenstein B, Germain V, Mongrand S.
Curr Opin Plant Biol. 2019 Sep 20;52:114-123. doi: 10.1016/j.pbi.2019.08.003.
88. Structural insights into the AapA1 toxin of Helicobacter pylori.
Korkut DN, Alves ID, Vogel A, Chabas S, Sharma CM, Martinez D, Loquet A, Salgado GF, Darfeuille F.
Biochim Biophys Acta Gen Subj. 2019 Aug 30:129423. doi: 10.1016/j.bbagen.2019.129423.
87. Molecular architecture of bacterial amyloids in Bacillus biofilms.
El Mammeri N, Hierrezuelo J, Tolchard J, Cámara-Almirón J, Caro-Astorga J, Álvarez-Mena A, Dutour A, Berbon M, Shenoy J, Morvan E, Grélard A, Kauffmann B, Lecomte S, de Vicente A, Habenstein B, Romero D, Loquet A.
FASEB J. 2019 Aug 5:fj201900831R. doi: 10.1096/fj.201900831R.
86. Tetrameric Aβ40 and Aβ42 β-Barrel Structures by Extensive Atomistic Simulations. II. In Aqueous Solution.
Nguyen PH, Campanera JM, Ngo ST, Loquet A, Derreumaux P.
J Phys Chem B. 2019 Aug 8;123(31):6750-6756. doi: 10.1021/acs.jpcb.9b05288.
85. A polymorphic helix of a Salmonella needle protein relays signals defining distinct steps in type III secretion.
Guo EZ, Desrosiers DC, Zalesak J, Tolchard J, Berbon M, Habenstein B, Marlovits T, Loquet A, Galán JE.
PLoS Biol. 2019 Jul 1;17(7):e3000351. doi: 10.1371/journal.pbio.3000351.
84. The extracellular matrix protects Bacillus subtilis colonies from Pseudomonas invasion and modulates plant co-colonization.
Molina-Santiago C, Pearson JR, Navarro Y, Berlanga-Clavero MV, Caraballo-Rodriguez AM, Petras D, García-Martín ML, Lamon G, Haberstein B, Cazorla FM, de Vicente A, Loquet A, Dorrestein PC, Romero D.
Nature Communications, 2019, Apr 23;10(1):1919. doi: 10.1038/s41467-019-09944-x.
83. Tetrameric Aβ40 and Aβ42 β-Barrel Structures by Extensive Atomistic Simulations. I. In a Bilayer Mimicking a Neuronal Membrane.
Nguyen PH, Campanera JM, Ngo ST, Loquet A, Derreumaux P.
J Phys Chem B., 2019, Apr 23. doi: 10.1021/acs.jpcb.9b01206
82. Structural and functional characterization of the Type Three Secretion System (T3SS) needle of Pseudomonas aeruginosa.
Lombardi C, Tolchard J, Bouillot S, Signor L, Gebus C, Liebl D, Fenel D, Teulon JM, Brock J, Habenstein B, Pellequer JL, Faudry E, Loquet A, Attree I, Dessen A, Job V.
Frontiers in Microbiology, 2019, Mar 29;10:573. doi: 10.3389/fmicb.2019.00573.
81. Molecular mechanisms for the destabilization of model membranes by islet amyloid polypeptide.
Divakara MB, Martinez D, Ravi A, Bhavana V, Ramana V, Habenstein B, Loquet A, Santosh MS.
Biophys Chem. 2019 Dec 14;245:34-40. doi: 10.1016/j.bpc.2018.12.002.
80. Avidity-driven polarity establishment via multivalent lipid-GTPase module interactions.
Meca J, Massoni-Laporte A, Martinez D, Sartorel E, Loquet A, Habenstein B, McCusker D.
EMBO J. 2019 Dec 17. pii: e99652. doi: 10.15252/embj.201899652.
2018
79. REM1.3’s phospho-status defines its plasma membrane nanodomain organization and activity in restricting PVX cell-to-cell movement
Perraki A, Gronnier J, Gouguet P, Boudsocq M, Deroubaix AF, Simon V, German-Retana S, Legrand A, Habenstein B, Zipfel C, Bayer E, Mongrand S, Germain V.
PLoS Pathog. 2018 Nov 12;14(11):e1007378. doi: 10.1371/journal.ppat.1007378
78. Functional Amyloids in Health and Disease
Loquet A, Saupe SJ, Romero D.
J Mol Biol. 2018 Jul 25. pii: S0022-2836(18)30850-7. doi:10.1016/j.jmb.2018.07.024.
77. 1H, 13C, 15N NMR resonance assignments and secondary structure determination of the extra-cellular domain from the human proapoptotic TRAIL-R2 death receptor 5 (DR5-ECD)
Baudin A, Guichard A, Collie GW, Rousseau S, Chaignepain S, Hocquellet A, Berbon M, Loquet A, Mackereth C, Guichard G, Odaert B.
Biomol NMR Assign. 2018 Oct;12(2):309-314. doi: 10.1007/s12104-018-9828-1
76. Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene.
Seuring C, Ayyer K, Filippaki E, Barthelmess M, Longchamp JN, Ringler P, Pardini T, Wojtas DH, Coleman MA, Dörner K, Fuglerud S, Hammarin G, Habenstein B, Langkilde AE, Loquet A, Meents A, Riek R, Stahlberg H, Boutet S, Hunter MS, Koglin J, Liang M, Ginn HM, Millane RP, Frank M, Barty A, Chapman HN.
Nat Commun. 2018 May 9;9(1):1836. doi: 10.1038/s41467-018-04116-9.
75. 3D Structure Determination of Amyloid Fibrils using Solid-State NMR Spectroscopy
Loquet A, El Mammeri N, Stanek J, Berbon M, Bardiaux B, Pintacuda G, Habenstein B
Methods 2018 Apr 5. pii: S1046-2023(17)30251-7. doi: 10.1016/j.ymeth.2018.03.014
74. Detection of side-chain proton resonances of fully protonated biosolids in nano-litre volumes by magic angle spinning solid-state NMR
Tolchard J. Pandey MK, Berbon M, Noubhani A, Saupe SJ, Nishiyama Y, Habenstein B, Loquet A
J Biomol NMR. 2018 Mar 3. doi: 10.1007/s10858-018-0168-3.
73. Coiled-coil oligomerization controls nanodomain organization of the plasma membrane REMORIN
Martinez D, Legrand A, Gronnier J, Decossas M, Gouguet P, Lambert O, Berbon M, Verron L, Grélard A, Germain V, Loquet A, Mongrand S, Habenstein B
J Struct Biol. 2018 Feb 23. pii: S1047-8477(18)30046-7. doi: 10.1016/j.jsb.2018.02.003.
72. Photodegradation of novel oral anticoagulants under sunlight irradiation in aqueous matrices
Yassine M, Fuster L, Dévier MH, Geneste E, Pardon P, Grélard A, Dufourc E, Al Iskandarani M, Aït-Aïssa S, Garric J, Budzinski H, Mazellier P, Trivella AS
Chemosphere. 2018 Feb;193:329-336. doi: 10.1016/j.chemosphere.2017.11.036.
71. The potent effect of mycolactone on lipid membranes.
Nitenberg M, Bénarouche A, Maniti O, Marion E, Marsollier L, Géan J, Dufourc EJ, Cavalier JF, Canaan S, Girard-Egrot AP.
PLoS Pathog. 2018 Jan 10;14(1):e1006814. doi: 10.1371/journal.ppat.1006814.
2017
70. Atomic Scale Structural Studies of Macromolecular Assemblies by Solid- state Nuclear Magnetic Resonance Spectroscopy
Loquet A, Tolchard J, Berbon M, Martinez D, Habenstein, B
J. Vis. Exp. 2017; (127), e55779, doi:10.3791/55779.
69. Structural Basis for Plant Plasma Membrane Protein Dynamics and Organization into Functional Nanodomains
Gronnier J, Crowet JM, Habenstein B, Nasir MN, Bayle V, Hosy E, Platre M, Gouguet P, Raffaele S, Martinez D, Grelard A, Loquet A, Simon-Plas F, Gerbeau-Pissot P, Der C, Bayer E, Jaillais Y, Deleu M, Germain V, Lins L, Mongrand S
Elife. 2017 Jul 31;6. pii: e26404. doi: 10.7554/eLife.26404.
68. Bacterial Filamentous Appendages Investigated by Solid-State NMR Spectroscopy.
Habenstein B, Loquet A.
Methods Mol Biol. 2017;1615:415-448. doi: 10.1007/978-1-4939-7033-9_29.
67. Lipid internal dynamics probed in nanodiscs
Martinez D, Decossas M, Kowal J, Frey L, Stahlberg H, Dufourc E, Riek R, Habenstein B, Bibow S, Loquet A
ChemPhysChem 2017 Jun 1. doi: 10.1002/cphc.201700450
66. Diversity of Amyloid Motifs in NLR Signaling in Fungi
Loquet A, Saupe S
Biomolecules 2017 Apr 13;7(2). pii: E38. doi: 10.3390/biom7020038
65. A two-component adhesive: Tau fibrils arise from a combination of a well-defined motif and conformationally flexible interactions.
Xiang S, Kulminskaya N, Habenstein B, Biernat J, Tepper K, Paulat M, Griesinger C, Becker S, Lange A, Mandelkow E, Linser R.
J. Am. Chem. Soc. 2017 Jan 26. doi: 10.1021/jacs.6b09619
2016
64. Identification of a novel cell death-inducing domain reveals that fungal amyloid-controlled programmed cell death is related to necroptosis.
Daskalov A, Habenstein B, Sabaté R, Berbon M, Martinez D, Chaignepain S, Coulary-Salin B, Hofmann K, Loquet A, Saupe SJ.
Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):2720-5. doi: 10.1073/pnas.1522361113.
63. Solid-state NMR: An emerging technique in structural biology of self-assemblies.
Habenstein B, Loquet A.
Biophys Chem. 2016 Mar;210:14-26. doi: 10.1016/j.bpc.2015.07.003.
62. Grape tannin catechin and ethanol fluidify oral membrane mimics containing moderate amounts of cholesterol: Implications on wine tasting?
Furlan AL, Saad A, Dufourc EJ, Géan J.
Biochimie. 2016 Nov;130:41-48. doi: 10.1016/j.biochi.2016.07.002.
61. Triggering bilayer to inverted-hexagonal nanostructure formation by thiol-ene click chemistry on cationic lipids: consequences on gene transfection.
Afonso D, Le Gall T, Couthon-Gourvès H, Grélard A, Prakash S, Berchel M, Kervarec N, Dufourc EJ, Montier T, Jaffrès PA.
Soft Matter. 2016 May 18;12(20):4516-20. doi: 10.1039/c6sm00609d.
60. Clouding in fatty acid dispersions for charge-dependent dye extraction.
Garenne D, Navailles L, Nallet F, Grélard A, Dufourc EJ, Douliez JP.
J Colloid Interface Sci. 2016 Apr 15;468:95-102. doi: 10.1016/j.jcis.2016.01.049.
59. Quantitative analysis of Bordeaux red wine precipitates by solid-state NMR: Role of tartrates and polyphenols.
Prakash S, Iturmendi N, Grelard A, Moine V, Dufourc E.
Food Chem. 2016 May 15;199:229-37. doi: 10.1016/j.foodchem.2015.12.013.
58. Self-Assembly of Bilayer Vesicles Made of Saturated Long Chain Fatty Acids.
Douliez JP, Houssou BH, Fameau AL, Navailles L, Nallet F, Grélard A, Dufourc EJ, Gaillard C.
Langmuir. 2016 Jan 19;32(2):401-10. doi: 10.1021/acs.langmuir.5b03627.
2015
57. Signal transduction by a fungal NOD-like receptor based on propagation of a prion amyloid fold.
Daskalov A, Habenstein B, Martinez D, Debets AJ, Sabaté R, Loquet A, Saupe SJ.
PLoS Biol. 2015 Feb 11;13(2):e1002059. doi: 10.1371/journal.pbio.1002059.
56. Hybrid Structure of the Type 1 Pilus of Uropathogenic Escherichia coli.
Habenstein B, Loquet A, Hwang S, Giller K, Vasa SK, Becker S, Habeck M, Lange A.
Angew Chem Int Ed Engl. 2015 Sep 28;54(40):11691-5. doi: 10.1002/anie.201505065.
55. β-Helical architecture of cytoskeletal bactofilin filaments revealed by solid-state NMR.
Vasa S, Lin L, Shi C, Habenstein B, Riedel D, Kühn J, Thanbichler M, Lange A.
Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):E127-36. doi: 10.1073/pnas.1418450112.
54. Hepatitis C Virus Envelope Glycoprotein E1 Forms Trimers at the Surface of the Virion.
Falson P, Bartosch B, Alsaleh K, Tews BA, Loquet A, Ciczora Y, Riva L, Montigny C, Montpellier C, Duverlie G, Pécheur EI, le Maire M, Cosset FL, Dubuisson J, Penin F.
J Virol. 2015 Oct;89(20):10333-46. doi: 10.1128/JVI.00991-15.
53. Structural heterogeneity in microcrystalline ubiquitin studied by solid-state NMR.
Fasshuber HK, Lakomek NA, Habenstein B, Loquet A, Shi C, Giller K, Wolff S, Becker S, Lange A.
Protein Sci. 2015 May;24(5):592-8. doi: 10.1002/pro.2654.
2014
52. High-resolution structure of the Shigella type-III secretion needle by solid-state NMR and cryo-electron microscopy.
Demers JP, Habenstein B, Loquet A, Kumar Vasa S, Giller K, Becker S, Baker D, Lange A, Sgourakis NG.
Nat Commun. 2014 Sep 29;5:4976. doi: 10.1038/ncomms5976.
51. Unlike twins: an NMR comparison of two α-synuclein polymorphs featuring different toxicity.
Gath J, Bousset L, Habenstein B, Melki R, Böckmann A, Meier BH.
PLoS One. 2014 Mar 5;9(3):e90659. doi: 10.1371/journal.pone.0090659.
50. BSH-CP based 3D solid-state NMR experiments for protein resonance assignment.
Shi C, Fasshuber HK, Chevelkov V, Xiang S, Habenstein B, Vasa SK, Becker S, Lange A.
J Biomol NMR. 2014 May;59(1):15-22. doi: 10.1007/s10858-014-9820-8.
49. Proton-detected MAS NMR experiments based on dipolar transfers for backbone assignment of highly deuterated proteins.
Chevelkov V, Habenstein B, Loquet A, Giller K, Becker S, Lange A.
J Magn Reson. 2014 May;242:180-8. doi: 10.1016/j.jmr.2014.02.020.
48. Yet another polymorph of α-synuclein: solid-state sequential assignments.
Gath J, Bousset L, Habenstein B, Melki R, Meier BH, Böckmann A.
Biomol NMR Assign. 2014 Oct;8(2):395-404. doi: 10.1007/s12104-013-9526-y.
47. Solid-state NMR sequential assignments of the amyloid core of Sup35pNM.
Luckgei N, Schütz AK, Habenstein B, Bousset L, Sourigues Y, Melki R, Meier BH, Böckmann A.
Biomol NMR Assign. 2014 Oct;8(2):365-70. doi: 10.1007/s12104-013-9518-y.
46. Solid-state NMR sequential assignments of the amyloid core of full-length Sup35p.
Schütz AK, Habenstein B, Luckgei N, Bousset L, Sourigues Y, Nielsen AB, Melki R, Böckmann A, Meier BH.
Biomol NMR Assign. 2014 Oct;8(2):349-56. doi: 10.1007/s12104-013-9515-1.
45. Aminosilane/oleic acid vesicles as model membranes of protocells.
Douliez JP, Zhendre V, Grélard A, Dufourc EJ.
Langmuir. 2014 Dec 16;30(49):14717-24. doi: 10.1021/la503908z.
44. Membrane lipids protected from oxidation by red wine tannins: a proton NMR study.
Furlan AL, Jobin ML, Buchoux S, Grélard A, Dufourc EJ, Géan J.
Biochimie. 2014 Dec;107 Pt A:82-90. doi: 10.1016/j.biochi.2014.07.008.
43. Red wine tannins fluidify and precipitate lipid liposomes and bicelles. A role for lipids in wine tasting?
Furlan AL, Castets A, Nallet F, Pianet I, Grélard A, Dufourc EJ, Géan J.
Langmuir. 2014 May 20;30(19):5518-26. doi: 10.1021/la5005006.
42. Solid-state NMR sequential assignments of the C-terminal oligomerization domain of human C4b-binding protein.
Luckgei N, Habenstein B, Ravotti F, Megy S, Penin F, Marchand JB, Hill F, Böckmann A, Meier BH.
Biomol NMR Assign. 2014 Apr;8(1):1-6. doi: 10.1007/s12104-012-9440-8.
2013
41. Atomic structure and handedness of the building block of a biological assembly.
Loquet A, Habenstein B, Chevelkov V, Vasa SK, Giller K, Becker S, Lange A.
J Am Chem Soc. 2013 Dec 26;135(51):19135-8. doi: 10.1021/ja411362q.
40. Structural and functional characterization of two alpha-synuclein strains.
Bousset L, Pieri L, Ruiz-Arlandis G, Gath J, Jensen PH, Habenstein B, Madiona K, Olieric V, Böckmann A, Meier BH, Melki R.
Nat Commun. 2013;4:2575. doi: 10.1038/ncomms3575.
39. Automated solid-state NMR resonance assignment of protein microcrystals and amyloids.
Schmidt E, Gath J, Habenstein B, Ravotti F, Székely K, Huber M, Buchner L, Böckmann A, Meier BH, Güntert P.
J Biomol NMR. 2013 Jul;56(3):243-54. doi: 10.1007/s10858-013-9742-x.
38. Cryogenic solid state NMR studies of fibrils of the Alzheimer’s disease amyloid-β peptide: perspectives for DNP.
Lopez del Amo JM, Schneider D, Loquet A, Lange A, Reif B.
J Biomol NMR. 2013 Aug;56(4):359-63. doi: 10.1007/s10858-013-9755-5.
37. The common structural architecture of Shigella flexneri and Salmonella typhimurium type three secretion needles.
Demers JP, Sgourakis NG, Gupta R, Loquet A, Giller K, Riedel D, Laube B, Kolbe M, Baker D, Becker S, Lange A.
PLoS Pathog. 2013 Mar;9(3):e1003245. doi: 10.1371/journal.ppat.1003245.
36. Structural investigations of molecular machines by solid-state NMR.
Loquet A, Habenstein B, Lange A.
Acc Chem Res. 2013 Sep 17;46(9):2070-9. doi: 10.1021/ar300320p. Review.
35. A straightforward method for stereospecific assignment of val and leu prochiral methyl groups by solid-state NMR: Scrambling in the [2-13C]Glucose labeling scheme.
Lv G, Faßhuber HK, Loquet A, Demers JP, Vijayan V, Giller K, Becker S, Lange A.
J Magn Reson. 2013 Mar;228:45-9. doi: 10.1016/j.jmr.2012.12.017.
34. Structural characterization of supramolecular assemblies by ¹³C spin dilution and 3D solid-state NMR.
Habenstein B, Loquet A, Giller K, Becker S, Lange A.
J Biomol NMR. 2013 Jan;55(1):1-9. doi: 10.1007/s10858-012-9691-9.
33. Mechanism of Trypanosoma brucei gambiense resistance to human serum.
Uzureau P, Uzureau S, Lecordier L, Fontaine F, Tebabi P, Homblé F, Grélard A, Zhendre V, Nolan DP, Lins L, Crowet JM, Pays A, Felu C, Poelvoorde P, Vanhollebeke B, Moestrup SK, Lyngsø J, Pedersen JS, Mottram JC, Dufourc EJ, Pérez-Morga D, Pays E.
Nature. 2013 Sep 19;501(7467):430-4. doi: 10.1038/nature12516.
32. Hepatitis B subvirus particles display both a fluid bilayer membrane and a strong resistance to freeze drying: a study by solid-state NMR, light scattering, and cryo-electron microscopy/tomography.
Grélard A, Guichard P, Bonnafous P, Marco S, Lambert O, Manin C, Ronzon F, Dufourc EJ.
FASEB J. 2013 Oct;27(10):4316-26. doi: 10.1096/fj.13-232843.
31. The enhanced membrane interaction and perturbation of a cell penetrating peptide in the presence of anionic lipids: toward an understanding of its selectivity for cancer cells.
Jobin ML, Bonnafous P, Temsamani H, Dole F, Grélard A, Dufourc EJ, Alves ID.
Biochim Biophys Acta. 2013 Jun;1828(6):1457-70. doi: 10.1016/j.bbamem.2013.02.008.
2012
30. Atomic model of the type III secretion system needle.
Loquet A, Sgourakis NG, Gupta R, Giller K, Riedel D, Goosmann C, Griesinger C, Kolbe M, Baker D, Becker S, Lange A.
Nature. 2012 May 20;486(7402):276-9. doi: 10.1038/nature11079. Erratum in: Nature. 2012 Aug 30;488(7413):684.
29. β-Sheet core of tau paired helical filaments revealed by solid-state NMR.
Daebel V, Chinnathambi S, Biernat J, Schwalbe M, Habenstein B, Loquet A, Akoury E, Tepper K, Müller H, Baldus M, Griesinger C, Zweckstetter M, Mandelkow E, Vijayan V, Lange A.
J Am Chem Soc. 2012 Aug 29;134(34):13982-9. doi: 10.1021/ja305470p.
28. Structure of a bacterial nanomachine: the type 3 secretion system needle.
Loquet A, Habenstein B, Demers JP, Becker S, Lange A.
Med Sci (Paris). 2012 Nov;28(11):926-8. doi: 10.1051/medsci/20122811008.
27. Solid-state NMR sequential assignments of α-synuclein.
Gath J, Habenstein B, Bousset L, Melki R, Meier BH, Böckmann A.
Biomol NMR Assign. 2012 Apr;6(1):51-5. doi: 10.1007/s12104-011-9324-3.
26. A native-like conformation for the C-terminal domain of the prion Ure2p within its fibrillar form.
Habenstein B, Bousset L, Sourigues Y, Kabani M, Loquet A, Meier BH, Melki R, Böckmann A.
Angew Chem Int Ed Engl. 2012 Aug 6;51(32):7963-6. doi: 10.1002/anie.201202093.
25. Conserved glycine 33 residue in flexible domain I of hepatitis C virus core protein is critical for virus infectivity.
Angus AG, Loquet A, Stack SJ, Dalrymple D, Gatherer D, Penin F, Patel AH.
J Virol. 2012 Jan;86(2):679-90. doi: 10.1128/JVI.05452-11.
24. Membrane interacting peptides: from killers to helpers.
Dufourc EJ, Buchoux S, Toupé J, Sani MA, Jean-François F, Khemtémourian L, Grélard A, Loudet-Courrèges C, Laguerre M, Elezgaray J, Desbat B, Odaert B.
Curr Protein Pept Sci. 2012 Nov;13(7):620-31. Review.
2011
23. 13C spin dilution for simplified and complete solid-state NMR resonance assignment of insoluble biological assemblies.
Loquet A, Lv G, Giller K, Becker S, Lange A.
J Am Chem Soc. 2011 Apr 6;133(13):4722-5. doi: 10.1021/ja200066s.
22. Extensive de novo solid-state NMR assignments of the 33 kDa C-terminal domain of the Ure2 prion.
Habenstein B, Wasmer C, Bousset L, Sourigues Y, Schütz A, Loquet A, Meier BH, Melki R, Böckmann A.
J Biomol NMR. 2011 Nov;51(3):235-43. doi: 10.1007/s10858-011-9530-4.
21. Pure α-metallated benzyllithium from a single-crystal-to-single-crystal transition.
Tatic T, Hermann S, John M, Loquet A, Lange A, Stalke D.
Angew Chem Int Ed Engl. 2011 Jul 11;50(29):6666-9. doi: 10.1002/anie.201102068.
20. Heteronuclear proton assisted recoupling.
De Paëpe G, Lewandowski JR, Loquet A, Eddy M, Megy S, Böckmann A, Griffin RG.
J Chem Phys. 2011 Mar 7;134(9):095101. doi: 10.1063/1.3541251.
19. Mechanism of inhibition of enveloped virus membrane fusion by the antiviral drug arbidol.
Teissier E, Zandomeneghi G, Loquet A, Lavillette D, Lavergne JP, Montserret R, Cosset FL, Böckmann A, Meier BH, Penin F, Pécheur EI.
PLoS One. 2011 Jan 25;6(1):e15874. doi: 10.1371/journal.pone.0015874.
18. Wheat-germ cell-free production of prion proteins for solid-state NMR structural studies.
Noirot C, Habenstein B, Bousset L, Melki R, Meier BH, Endo Y, Penin F, Böckmann A.
N Biotechnol. 2011 Apr 30;28(3):232-8. doi: 10.1016/j.nbt.2010.06.016.
17. Key role of polyphosphoinositides in dynamics of fusogenic nuclear membrane vesicles.
Zhendre V, Grélard A, Garnier-Lhomme M, Buchoux S, Larijani B, Dufourc EJ.
PLoS One. 2011;6(9):e23859. doi: 10.1371/journal.pone.0023859.
2010
16. Supramolecular interactions probed by 13C-13C solid-state NMR spectroscopy.
Loquet A, Giller K, Becker S, Lange A.
J Am Chem Soc. 2010 Nov 3;132(43):15164-6. doi: 10.1021/ja107460j.
15. Protocols for the sequential solid-state NMR spectroscopic assignment of a uniformly labeled 25 kDa protein: HET-s(1-227).
Schuetz A, Wasmer C, Habenstein B, Verel R, Greenwald J, Riek R, Böckmann A, Meier BH.
Chembiochem. 2010 Jul 26;11(11):1543-51. doi: 10.1002/cbic.201000124.
14. Atomic-resolution three-dimensional structure of HET-s(218-289) amyloid fibrils by solid-state NMR spectroscopy.
Van Melckebeke H, Wasmer C, Lange A, Ab E, Loquet A, Böckmann A, Meier BH.
J Am Chem Soc. 2010 Oct 6;132(39):13765-75. doi: 10.1021/ja104213j.
13. NMR spectroscopy of lipid bilayers.
Grélard A, Loudet C, Diller A, Dufourc EJ.
Methods Mol Biol. 2010;654:341-59. doi: 10.1007/978-1-60761-762-4_18.
12. Biphenyl phosphatidylcholine: a promoter of liposome deformation and bicelle collective orientation by magnetic fields.
Loudet C, Diller A, Grélard A, Oda R, Dufourc EJ.
Prog Lipid Res. 2010 Jul;49(3):289-97. doi: 10.1016/j.plipres.2010.02.002. Review.
2009
11. Prion fibrils of Ure2p assembled under physiological conditions contain highly ordered, natively folded modules.
Loquet A, Bousset L, Gardiennet C, Sourigues Y, Wasmer C, Habenstein B, Schütz A, Meier BH, Melki R, Böckmann A.
J Mol Biol. 2009 Nov 20;394(1):108-18. doi: 10.1016/j.jmb.2009.09.016.
10. Characterization of different water pools in solid-state NMR protein samples.
Böckmann A, Gardiennet C, Verel R, Hunkeler A, Loquet A, Pintacuda G, Emsley L, Meier BH, Lesage A.
J Biomol NMR. 2009 Nov;45(3):319-27. doi: 10.1007/s10858-009-9374-3.
9. The molecular organization of the fungal prion HET-s in its amyloid form.
Wasmer C, Schütz A, Loquet A, Buhtz C, Greenwald J, Riek R, Böckmann A, Meier BH.
J Mol Biol. 2009 Nov 20;394(1):119-27. doi: 10.1016/j.jmb.2009.09.015.
8. Nucleotide-promoted morphogenesis in amphiphile assemblies: kinetic control of micrometric helix formation.
Aimé C, Tamoto R, Satoh T, Grelard A, Dufourc EJ, Buffeteau T, Ihara H, Oda R.
Langmuir. 2009 Aug 4;25(15):8489-96. doi: 10.1021/la8043297.
7. Bicelles: A natural ‘molecular goniometer’ for structural, dynamical and topological studies of molecules in membranes.
Diller A, Loudet C, Aussenac F, Raffard G, Fournier S, Laguerre M, Grélard A, Opella SJ, Marassi FM, Dufourc EJ.
Biochimie. 2009 Jun;91(6):744-51. doi: 10.1016/j.biochi.2009.02.003. Review.
6. Solution and solid-state NMR of lipids.
Grelard A, Couvreux A, Loudet C, Dufourc EJ.
Methods Mol Biol. 2009;462:111-33. doi: 10.1007/978-1-60327-115-8_7.
2008
5. Methyl proton contacts obtained using heteronuclear through-bond transfers in solid-state NMR spectroscopy.
Loquet A, Laage S, Gardiennet C, Elena B, Emsley L, Böckmann A, Lesage A.
J Am Chem Soc. 2008 Aug 13;130(32):10625-32. doi: 10.1021/ja801464g.
4. Proton assisted recoupling and protein structure determination.
De Paëpe G, Lewandowski JR, Loquet A, Böckmann A, Griffin RG.
J Chem Phys. 2008 Dec 28;129(24):245101. doi: 10.1063/1.3036928.
3. Polarization transfer over the water-protein interface in solids.
Lesage A, Gardiennet C, Loquet A, Verel R, Pintacuda G, Emsley L, Meier BH, Böckmann A.
Angew Chem Int Ed Engl. 2008;47(31):5851-4. doi: 10.1002/anie.200801110.
2. Structural constraints for the Crh protein from solid-state NMR experiments.
Gardiennet C, Loquet A, Etzkorn M, Heise H, Baldus M, Böckmann A.
J Biomol NMR. 2008 Apr;40(4):239-50. doi: 10.1007/s10858-008-9229-3.
1. 3D structure determination of the Crh protein from highly ambiguous solid-state NMR restraints.
Loquet A, Bardiaux B, Gardiennet C, Blanchet C, Baldus M, Nilges M, Malliavin T, Böckmann A.
J Am Chem Soc. 2008 Mar 19;130(11):3579-89. doi: 10.1021/ja078014t.